Anemone study: prevalence of risk factors for superficial vein thrombosis in a large Italian population of blood donors.

Autor: Grandone, Elvira, Tiscia, Giovanni Luca, Ostuni, Angelo, di Mauro, Lazzaro, Mastroianno, Mario, Coffetti, Nadia, Dovigo, Roberto, Meneghini, Giovanna, Turrini, Anna, Cavallero, Giobatta, Cappucci, Filomena, Vergura, Patrizia, De Laurenzo, Antonio, Tosetto, Alberto, Margaglione, Maurizio
Zdroj: Journal of Thrombosis & Thrombolysis; Oct2020, Vol. 50 Issue 3, p689-696, 8p
Abstrakt: Knowledge of the distribution of risk factors for superficial thrombosis (SVT) in low-risk population is fundamental to improve the prevention of the disease in each individual and high-risk settings of patients. Exact frequency data for the low-risk population are scarce, but could be useful for optimal use of prophylactic strategies against venous thrombosis. Blood donors represent a low-risk population, because are healthier than the general population. The objective of this study was to assess the prevalence of vein thrombosis, particularly SVT, and associated risk factors in a low-risk population such as blood donors. In this multicentre cross-sectional study, donors from six Italian blood banks responded to a self-administered questionnaire. The enrolment lasted from 1st June 2017 to 30th July 2018. History of vein thrombosis was referred by 89 (0.76%) individuals, (49 men) with an age-dependent effect. The prevalence reached 2.9% in women and 0.8% in men aged ≥ 49 years, with a significant difference only for women. After controlling for potential confounders, a significant and independent association was found between a history of vein thrombosis and age (OR: 1.03, 95%CI 1.01–1.05), varicose veins (OR: 15.8, 95%CI 7.7–32.6), plaster cast/bed rest (OR: 2.3, 95% CI 1.0–5.3) and transfusion (OR: 5.1, 95% CI 1.3–19.5). This study shows that low-risk individuals share the same risk factors for SVT as patients in secondary care. It also suggests that transfusion confers an increased risk of SVT in healthy population. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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