| Autor: |
Takikawa, Hiroshi, Murata, Kazuki, Sato, Shogo, Kawada, Takuma, Nakakohara, Hiroshi, Ohmori, Ken, Suzuki, Keisuke |
| Předmět: |
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| Zdroj: |
Synlett; 2020, Vol. 31 Issue 16, p1623-1628, 6p |
| Abstrakt: |
Toward a stereoselective total synthesis of the lactonamycins, we recently reported an approach to the DEF-ring system. Here we report a model study for constructing the ABCD-ring system, revealing a viable approach through (1) construction of the C-ring by asymmetric benzoin cyclization, (2) introduction of an angular hydroxy group through oxidation of an isoxazolium salt, and (3) construction of the AB rings through a ring-opening/closing sequence. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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