| Abstrakt: |
Aim: One of the fundamental aims in endodontics is complete disinfection of the root canal. Medicinal plant extracts had effective antibacterial activity with less side effects and low cost. The aims of this study were to compare and evaluate the in vitro and in vivo antibacterial activity of different plants extracts (Ficus carica latex [FX], F. carica leaves [FL], olive leaves [OL], and Salvadora persica [SP] roots) and 2% chlorhexidine against Enterococcus faecalis when they are used as intracanal medicaments. Materials and Methods: The antibacterial effect of FX, (2%, 4%, and 8%) FL, (2%, 4%, and 8%) OL, (2%, 4%, and 8%) SP, 2% chlorhexidine (CHX), and normal saline (NS) were evaluated in vitro against E. faecalis by broth microdilution method. Sixty single-rooted teeth were selected for the in vivo study. First pretreatment sample was obtained immediately after access opening. After the instrumentation of the canals, second post-instrumentation sample was taken. Then, teeth were divided into six groups (n = 10/group), Group I: NS, Group II: 2% CHX, Group III: FX, Group IV: 8% FL, Group V: 8% OL, and Group VI: 8% SP. After 7 days, post-medication sample was collected. Analysis of variance and Tukey post hoc tests were used for statistical analysis at P = 0.05. Results: All plant extracts at 8% and 2% CHX showed significant antibacterial effect against E. faecalis both in vitro and in vivo, and significantly not different. Conclusion: Under the limitation of this study, it can be concluded that FL and ethanolic extracts of 8% FL, 8% OL, and 8% SP roots were effective for the elimination of E. faecalis. Therefore, they can be used as alternative intracanal medicaments. [ABSTRACT FROM AUTHOR] |
