| Autor: |
Othman, Haitham Fekry, El-Khatib, Ahmed Fouad, Shehata, Samy Ramzy |
| Předmět: |
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| Zdroj: |
Indian Journal of Public Health Research & Development; Mar2020, Vol. 11 Issue 3, p2572-2577, 6p |
| Abstrakt: |
Background: The standard abdomino-perineal excision (SAPE) is associated with a high incidence of Intraoperative Bowel Perforation (IOBP) and positive circumferential resection margin (CRM), both are major determinants of local recurrence. This led to the introduction of the more radical surgery; extra levator abdomino-perineal excision (ELAPE). Method: This prospective pilot study included 40 patients with low rectal cancer. They were randomized to either ELAPE Group or SAPE Group. The study was carried out over 54 months, from January 2014 to June 2018. All patients were evaluated regarding operative factors, early postoperative complications, and oncological outcomes (CRM and local recurrence). Results: IOBP Occurred in one patient in ELAPE Group (5%) vs. seven in SAPE Group (35%) (p=0.044). CRM was positive in seven patients of the SAPE group (35%) vs. one (5%) in the ELAPE group (p=0.004). Local recurrence occurred in six patients (30%) of the SAPE group vs. one (5%) in the ELAPE group (p=0.091). There was no significant difference between the two groups regarding perineal wound complications, urinary complications, Operative factors, and Length of Hospital Stay (LHS). Conclusion: ELAPE is an oncologically superior and equally safe procedure to replace SAPE without compromising patients’ QOL. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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