Urine Serotonin in Sleep Deprivation Children.

Autor: Umamah, Irwanto, Saharso, Darto
Předmět:
Zdroj: Indian Journal of Public Health Research & Development; Mar2020, Vol. 11 Issue 3, p2522-2527, 6p
Abstrakt: Background: Sleep deprivation can cause significant medical and behaviour morbidities. Many factors influenced sleep deprivation. One of the biological factors that influenced sleep deprivation was serotonin that was not clearly understood yet. 5-HIAA was serotonin metabolite, the increasement in urine reflect whole body serotonin increasement. Objective: To analize correlation between urine serotonin and sleep deprivation. Method Cross sectional study was done in Airlangga I Elementary School Surabaya, Indonesia, subjects children 6-10 years old. They were screened by The Children’s Sleep Habits Questionnaire-Abbreviated (CSHQ-A) developed by Owen et al., to assess sleep deprivation. The same number children without sleep deprivation was taken as a control group. They were collecting 24 hours urine, then measured urine serotonin level (ELISA method). Data were analyzed with Chi-square test, and Spearman Correlation Test, significant p value<0.05. Results: One hundred sixty four children were screened by CSHQ-A, 15% categorized as sleep deprivation. Fourteen children (90%) with sleep deprivation came from low socioeconomic family. There was no significant differences in urine serotonin level between children with and without sleep deprivation (p 0.933). There was weak correlation between sleep deprivation and urine serotonin level in subjects with low socioeconomic status (r 0.089). Conclusion: No differences about urine serotonin in children with and without sleep deprivation. Children with poor socioeconomic family tend to have more sleep problems. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index