The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy.

Autor: Baptista, Frederico R., Devereux, Stephen J., Gurung, Sarah P., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Brazier, John A., Kelly, John M., Quinn, Susan J.
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Zdroj: Chemical Communications; 8/28/2020, Vol. 56 Issue 67, p9703-9706, 4p
Abstrakt: Ultrafast time resolved infrared (TRIR) is used to report on the binding site of the "light-switch" complex [Ru(phen)2(dppz)]2+1 to i-motif structures in solution. Detailed information is provided due to perturbation of the local base vibrations by a 'Stark-like' effect which is used to establish the contribution of thymine base loop interactions to the binding site of 1 in this increasingly relevant DNA structure. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index