| Autor: |
Lin, Sophia D, Butler, Jane E, Boswell-Ruys, Claire L, Hoang, Phu D, Jarvis, Tom, Gandevia, Simon C, McCaughey, Euan J |
| Předmět: |
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| Zdroj: |
Multiple Sclerosis Journal - Experimental, Translational & Clinical; 8/6/2020, Vol. 6 Issue 2, p1-9, 9p |
| Abstrakt: |
Background: Chronic constipation is prevalent in people with multiple sclerosis, with current treatments usually only partially effective. Objectives: This study aims to evaluate the efficacy of abdominal functional electrical stimulation to reduce whole gut and colonic transit times and improve bowel and bladder-related quality of life. Methods: A total of 23 people with multiple sclerosis who fulfilled the Rome III criteria for functional constipation applied abdominal functional electrical stimulation for 1 hour per day, 5 days per week, for 6 weeks. Whole gut and colonic transit times and bowel and bladder-related quality of life were measured before and after the intervention period. Results: Whole gut (mean 81.3 (standard deviation 28.7) hours pre vs. 96.1 (standard deviation 53.6) hours post-intervention, P = 0.160) and colonic transit time (65.1 (31.4) vs. 74.8 (51.1) hours, P = 0.304) were unchanged following 6 weeks of abdominal functional electrical stimulation. There was a significant improvement in bowel (mean 1.78 (SD: 0.64) pre vs. 1.28 (SD: 0.54) post, P = 0.001) and bladder (50.6 (26.49) vs. 64.5 (21.92), p = 0.007) related quality of life after the intervention period. Conclusion: While abdominal functional electrical stimulation did not reduce whole gut and colonic transit times for people with multiple sclerosis, a significant improvement in bowel and bladder-related quality of life was reported. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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