| Autor: |
Rakesh, K., Naik, M. Ganapathi, Pinto, Nevil, Shankar, K. M., Kumar, B. T. Naveen, Poojary, Satish Rama, Abhiman, P. B. |
| Předmět: |
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| Zdroj: |
Journal of Experimental Zoology India; Jul2020, Vol. 23 Issue 2, p1783-1789, 7p |
| Abstrakt: |
Efficacy of oxolinic acid against Vibrio parahaemolyticus was evaluated in Litopenaeus vannamei. Among the three dosages feed containing 2, 4 and 6.65g oxolinic acid/kg feed, a dosage of 2g oxolinic acid/kg feed for 3 days was found to be effective against V. parahaemolyticus in L. vannamei. Further elimination of the oxolinic acid was studied by feeding healthy shrimps with 2 g oxolinic acid/kg of feed at the rate of 3% of body weight. Muscle and hepatopancreas samples were collected at 1, 2, 3, 5, 7, 9, 11, 13 and 15th day after 3 days of medication period. Antibiotic residue was analysed by High Performance Liquid Chromatography (HPLC). The maximum concentration (Cmax) of oxolinic acid was found in hepatopancreas (1.99μg/g) compared to muscle (1.04μg/g) at 16 h post feeding. On the 15th day, concentration of oxolinic acid in muscle tissue and hepatopancreas found to be 0.15 μg/g and 0.12μg/g, respectively. In the present study, concentration of oxolinic acid did not exceed the maximum residue level limit of 0.3 ppm in both muscle and hepatopancreas. It was found that the withdrawal time of oxolinic acid is 15 days after the cessation of medicated feeding when the residual concentrations in both tissues become less than maximum residual limit and thus safe for human consumption. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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