| Autor: |
Kumar, Putha Suman, Srinivas, Challapalli, Vadhiraja, B. M., Banerjee, Sourjya, Shreyas, R., Saxena, P. U. Prakash, Ravichandran, Ramamoorthy, Lobo, Dilson |
| Předmět: |
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| Zdroj: |
Journal of Medical Physics; Apr-Jun2020, Vol. 45 Issue 2, p123-129, 7p |
| Abstrakt: |
Purpose: The aim of this study is to estimate delivered radiation doses inside planning tumor volume (PTV) using the in vivo (mid-plane dose) measurement and transit measurement methods in gynecological malignancy patients undergoing three-dimensional conformal radiotherapy (3DCRT) using calibrated ionization chambers. Materials and Methods: Six patients with histopathologically proven carcinoma of the cervix or endometrium were planned with four-field 3DCRT to the pelvic site. Isocenter was at the geometric mid-plane of PTV with a dose prescription of 50 Gy in 25 fractions. Clinical mid-plane dose (Diso, Transit) estimates were done in one method (transit) using the FC-65 positioned at electronic portal imaging device level. In another method, a repeat computerized tomography scan was performed (at the 11th fraction) using CC-13 having a protective cap in the vaginal cavity for in vivo measurements (Din vivo). Simultaneous measurements were performed with the two chambers from the 11th fraction onward at least 3-4 times during the remaining course of treatment. Results: The agreement of mean doses from these two described methods and treatment planning system reference doses was in the range of -4.4 ± 1.1% (minimum) to -0.3 ± 2.0% (maximum) and -4.0 ± 1.7% (minimum) to 1.9 ± 2.4% for Din vivo and Diso, Transit, respectively, which are an acceptable range of daily radiation dose delivery. Conclusion: The fundamental importance of this study lies in simultaneous validation of delivered dose in real time with two methods. A study in this small number of patients has given the confidence to apply transit measurements for quality assurance on a routine basis as an accepted clinical dosimetry for the selected patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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