Carbapenam resistance in Klebsiella Pneumoniae: An Overview.

Autor: Patil, Praful S., Shah, Harshada, Damke, Smita, Chandel, M. S.
Předmět:
Zdroj: Indian Journal of Basic & Applied Medical Research; Jun2020, Vol. 9 Issue 3, p103-113, 11p
Abstrakt: In recent years, antibiotic resistance has become a serious threat to public health as bacteria are increasingly developing resistance to antibiotics while drug manufacturing companies are not developing new antibiotics that can compact the menace of drug resistance. Carbapenems are among the most effective antibiotics prescribed for treatment of life threatening infections caused by gram negative bacteria including Enterobacteriaceae. However in recent times, carbapenem resistance in Enterobacteriaceae is an ongoing public-health globally. Klebsiella pneumoniae is one of the most common isolate from Enterobacteriaceae. It causes variety of infections including health care associated infections. In recent years, K. pneumoniae has developed resistance to multiple antibiotics including extended spectrum β-lactam and carbapenem antimicrobial agents. In this present review article, the overview of carbapenam resistance in K. Pneumoniae is presented with emphasis on historical perspectives, epidemiology, laboratory identification and prevention and control. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index