| Autor: |
Durán, Josefina, Massardo, Loreto, Llanos, Carolina, Iacobelli, Sergio, Burgos, Paula I, Cisternas, Marcela, Iruretagoyena, Mirentxu, Armstrong, Macarena, Aguilera, Raquel, Radrigán, Francisco, Martinez, María Eugenia, Passi-Solar, Alvaro, Riedemann, Pablo, Crisóstomo, Natalia, Cifuentes, Camila, Hagedorn, Lucero, Cisternas, Alvaro, Vasquez, Nancy, Margozzini, Paula, the ENS2017 Study Group |
| Předmět: |
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| Zdroj: |
Journal of Rheumatology; Jul2020, Vol. 47 Issue 7, p951-958, 8p |
| Abstrakt: |
Objective: Genetic and environmental backgrounds influence the development of rheumatoid arthritis (RA). In Latin America, epidemiologic data are scarce. We aimed to determine the prevalence of RA in Chile in a population-based study.Methods: The National Health Survey was a cross-sectional household survey with a stratified multistage probability sample of 6233 participants performed between August 2016 and March 2017. A screening instrument for RA was applied to a random sample of 3847 subjects > 30 years old. Positive screening was defined by at least 1 of the following: 2 swollen joints for at least 4 consecutive weeks (past/present), and/or a diagnosis of arthritis in the past. Individuals with positive screening had rheumatoid factor, anticitrullinated protein antibodies, and C-reactive protein measured, as well as clinical examination performed by a rheumatologist. Self-report of doctor-diagnosed RA was also performed.Results: The screening questionnaire was applied to 2998 subjects. A positive screening was found for 783 (22.1%). Among subjects with positive screening, 493 (66%) had a clinical evaluation performed by a rheumatologist. Using the American College of Rheumatology/European League Against Rheumatism 2010 classification criteria, prevalence was 0.6% (95% CI 0.3-1.2). Prevalence was higher in women, and 3.3% of subjects self-reported having RA.Conclusion: According to this national population-based study, RA prevalence in Chile is 0.6% (0.3-1.2), a value similar to what has been found in developed countries and slightly lower than some Latin American countries. Self-reporting leads to overestimating RA. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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