SCREENING OF ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES OF GREEN MICROALGA Coelastrella sp. BGV.

Autor: TOSHKOVA-YOTOVA, T., ALEXANDROV, S., PILARSKI, P., YOCHEVA, L., PETROVA, D., CHANEVA, G.
Předmět:
Zdroj: Oxidation Communications; 2020, Vol. 43 Issue 2, p265-279, 15p
Abstrakt: The screening of four green microalgal strains of genus Coelastrella - Coelastrella sp. BGV, Coelastrella multistriata var. corcontica (CCALA 308), Coelastrella multistriata var. multistriata (CCALA 309) and Coelastrella vacuolata (CCALA 356) showed that Coelastrella sp. BGV - a newly isolated Bulgarian strain, had the highest growth potential under laboratory conditions. The favourable biomass composition (proteins - 35.32%, carbohydrates - 38.66% and lipids - 13.9%) gave us a reason to consider that strain as biotechnologically promising and to investigate its antimicrobial and antioxidant properties. The ethanol extract obtained from Coelastrella sp. BGV biomass exhibited the highest antimicrobial activity - it was effective against six of the nine test-microorganisms (2 Gram-positive and 7 Gram-negative bacteria). The fatty acid mixture inhibited the development of four bacterial strains, followed by the polysaccharide fraction and culture medium fluid. Pseudomonas aeruginosa, Proteus mirabilis and Escherichia coli UPEC proved to be the most sensitive. All algal products were active against Candida albicans, and the strongest antifungal effect was shown with ethanol extracts and fatty acids, Studying the antioxidant properties, we found that the ethanol extract contained enhanced phenol (279 mg g-1 DW) and flavonoid content (84.3 mg g-1 DW). The increased total antioxidant activity (238.5 mM g-1 DW) might also indicate that ethanol extract has a high bioactive potential and therefore, more in-depth study to characterise its biochemical composition is needed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index