Autor: |
Kondo, Hinako, Watanabe, Ryu, Okazaki, Soshi, Kuriyama, Kaori, Ochi, Tetsuro, Yamada, Gen, Sugiura, Akira, Chiba, Hiromu, Tsukada, Akira, Taniuchi, Shinji, Igarashi, Takehiko, Kudo, Masataka, Harigae, Hideo, Fujii, Hiroshi |
Předmět: |
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Zdroj: |
Modern Rheumatology Case Reports; Jul2020, Vol. 4 Issue 2, p289-295, 7p |
Abstrakt: |
We report a case of polycythaemia vera (PV) associated with IgA vasculitis. A 45-year-old man was admitted for evaluation of abdominal pain and palpable purpura. IgA vasculitis was diagnosed, and oral prednisolone therapy (30 mg/day) was initiated. On day 6, the patient developed left hemiparesis, and magnetic resonance imaging revealed acute cerebral infarction. Bone marrow biopsy results and the identification of a Janus kinase 2 (JAK2) mutation led to the diagnosis of PV. Despite steroid therapy, urine protein levels increased to 15 g/g・Cre. Renal biopsy demonstrated mild mesangial proliferation with IgA deposits, but immunosuppressive therapy was partially effective. This case suggests that PV can be a complication of IgA vasculitis and that preventive measures for thrombosis should be taken in such cases. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
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