The Number of Harvested LNs Is an Independent Prognostic Factor in Lymph Node Metastasis-negative Patients Who Received Curative Esophagectomy.

Autor: TORU AOYAMA, YOSUKE ATSUMI, SHINNOSUKE KAWAHARA, HIROSHI TAMAGAWA, AYAKO TAMAGAWA, YUKIO MAEZAWA, KAZUKI KANO, MASAAKI MURAKAWA, KEISUKE KAZAMA, MASAKATSU NUMATA, TAKASHI OSHIMA, NORIO YUKAWA, MUNETAKA MASUDA, YASUSHI RINO
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Zdroj: In Vivo; Jul/Aug2020, Vol. 34 Issue 4, p2021-2027, 7p
Abstrakt: Background/Aim: The aim of the present study was to evaluate the optimal number of harvested LNs (LNs) in patients who were LN metastasis-negative after curative esophagectomy for esophageal cancer. Patients and Methods: Sixty-one patients who underwent curative surgery for esophageal cancer between 2005 and 2017 and diagnosed as lymph node metastasis-negative were included in this study. Results: The 5-year overall survival rates were 27.8% for 0-20 harvested LNs, 35.7% for 21-30 harvested LNs, 79.4% for 31-40 harvested LNs, and 85.2% for ≥41 harvested LNs. Thirty harvested LNs was regarded as the optimal critical point of classification, considering the 5year OS rate. The number of harvested LNs was selected as a significant prognostic factor in both univariate and multivariate analyses. The respective 3-and 5-year OS rates were 50.3% and 36.7% for <30 harvested LNs and 82.4% and 82.4% for ≥30 harvested LNs (p=0.003). Conclusion: Thirty or more harvested LNs was a significant prognostic factor in patients with metastasis-negative LNs after curative esophagectomy for esophageal cancer. Therefore, the number of harvested LNs might be useful for predicting the LN metastasis status in esophageal cancer. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index