Surgical ventricular restoration—meta-analysis of observational studies.

Autor: Adhyapak, Srilakshmi Mandayam, Menon, Prahlad Gopalakrishna, Parachuri, Venkateswara Rao, Michael, John, Thomas, Tinku
Zdroj: Indian Journal of Thoracic & Cardiovascular Surgery; Jul2020, Vol. 36 Issue 4, p347-355, 9p
Abstrakt: Background: Technique of surgical ventricular restoration (SVR) may impact its outcomes. Therefore, we conducted a meta-analysis of studies on SVR performed by using different techniques and studied outcomes. Methods: Scientific databases were searched for studies on SVR. End points assessed were NYHA class, left ventricular ejection fraction (LVEF), end-systolic volume index (ESVI), sphericity index, apical rotations, mortality, and re-admissions for heart failure. Results: Circular patch use showed significant increases in LVEF by 9.53% (7.62, 11.45), decreases in ESVI by − 35.16 ml (− 44.97, − 25.34), improvements in NYHA class by − 1.29 (− 1.45, − 1.13), and decreases in sphericity index by − 0.04 (− 0.08, 0.00). In studies using rectangular patch, the LVEF showed an increase by 5.75% (3.52, 7.98,), the NYHA class improved by − 2.45 (− 2.59, − 2.32). The decrease in ESVI was − 40.36 ml (− 62.2, − 18.52). The apical rotation increased by 3.450(0.62, 6.29,). Re-admission for heart failure and mortality was less. When the magnitude of ESVI decrease were compared within studies using rectangular patch, the greatest decrease in ESVI was notedwith use of a rectangular patch. (− 59 ml versus − 40 ml a very narrow patch and − 22 ml use of oval patch) The improvements in sphericity index at 2 years in use of rectangular patch study was − 0.78 ± 0.11 versus 0.00 ± 0.03 in use of oval patch study. Conclusions: Rectangular patch use resulted in maximal decreases in ESVI and sphericity index. Mortality and re-admissions for heart failure were also significantly less at mid-term after SVR. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index