Simple change in logistic procedure improves response rate to QOL assessment: a report from the Japan Children's Cancer Group.

Autor:	Sato, Iori, Soejima, Takafumi, Ishida, Yasushi, Maeda, Miho, Koh, Katsuyoshi, Kamibeppu, Kiyoko
Předmět:	CANCER QUALITY of life CLINICAL trials MEDICAL care CANCER patients STATISTICS CONFIDENCE intervals HEALTH outcome assessment REGRESSION analysis TUMORS in children PRE-tests & post-tests DESCRIPTIVE statistics QUESTIONNAIRES RESEARCH funding DATA analysis ODDS ratio SECONDARY analysis EVALUATION
Zdroj:	Journal of Patient-Reported Outcomes; 6/17/2020, Vol. 4 Issue 1, p1-5, 5p
Abstrakt:	Background: Reducing non-completion of quality-of-life assessment in clinical trials is an important challenge in obtaining accurate data and unbiased interpretation of patients' quality-of-life for each regimen. We evaluated the effect of changing our questionnaire distribution procedure in a multicenter phase II/III trial on the response rate to a quality-of-life questionnaire. Methods: In the trial, we distributed 1767 questionnaires and 1045 were returned. We adopted a regression discontinuing design and estimated the change in response rate between pre-intervention (quality-of-life questionnaires were sent to each center soon after patient registration) and post-intervention (a set of tailored questionnaires was sent just before the first quality-of-life assessment). Results: The post-intervention response rate was higher (odds ratio = 1.62) than the pre-intervention response rate. Conclusions: A simple logistic intervention reduced the non-completion of QOL assessment in this case, suggesting that a simple change can contribute to improving clinical trial accomplishment. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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