| Autor: |
Chen, Mason T., Mahmood, Faisal, Sweer, Jordan A., Durr, Nicholas J. |
| Předmět: |
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| Zdroj: |
IEEE Transactions on Medical Imaging; Jun2020, Vol. 39 Issue 6, p1988-1999, 12p |
| Abstrakt: |
We present a deep learning framework for wide-field, content-aware estimation of absorption and scattering coefficients of tissues, called Generative Adversarial Network Prediction of Optical Properties (GANPOP). Spatial frequency domain imaging is used to obtain ground-truth optical properties at 660 nm from in vivo human hands and feet, freshly resected human esophagectomy samples, and homogeneous tissue phantoms. Images of objects with either flat-field or structured illumination are paired with registered optical property maps and are used to train conditional generative adversarial networks that estimate optical properties from a single input image. We benchmark this approach by comparing GANPOP to a single-snapshot optical property (SSOP) technique, using a normalized mean absolute error (NMAE) metric. In human gastrointestinal specimens, GANPOP with a single structured-light input image estimates the reduced scattering and absorption coefficients with 60% higher accuracy than SSOP while GANPOP with a single flat-field illumination image achieves similar accuracy to SSOP. When applied to both in vivo and ex vivo swine tissues, a GANPOP model trained solely on structured-illumination images of human specimens and phantoms estimates optical properties with approximately 46% improvement over SSOP, indicating adaptability to new, unseen tissue types. Given a training set that appropriately spans the target domain, GANPOP has the potential to enable rapid and accurate wide-field measurements of optical properties. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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