| Autor: |
Dhineshkumar, E., doss, M. Arockia, Uma, D. |
| Předmět: |
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| Zdroj: |
World News of Natural Sciences (WNOFNS); 2020, Vol. 30, p214-223, 10p |
| Abstrakt: |
In the present study of 4,5-diphenyl-1-((tetrahydrofuran-2-yl)methyl)-2-(3,4,5-trichlorophenyl)- ¹H-imidazole 1 was synthesized. The synthesized imidazole compound 1 has been characterized by FTIR, ¹H, 13C NMR and ESI-Mass spectral studies. Molecular docking is also performed in order to explain the over expression of estrogen receptor in 70% of liver cancer. The imidazole scaffold is a privileged scaffold for exploration of anticancer agents. The objective of the present study is to evaluate the anticancer activity of imidazole 1 in human liver cancer cell lines HepG2. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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