| Autor: |
Awad, H. A., Mahmoud, M. Z., Aboelwafa, M. S., Shabana, A. M., Shehata, B. M., Ahmed, W. O., Ismail, R. I. H., Imam, Safaa S. |
| Předmět: |
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| Zdroj: |
QJM: An International Journal of Medicine; 2020 Supplement, Vol. 113, pi212-i213, 2p |
| Abstrakt: |
We report the use of Levosimendan, calcium sensitizer, inodilator in a neonate with post-operative refractory cardiogenic shock. Currently, no data are available on the use of levosimendan in newborns outside the cardiosurgical setting. A 38-week neonate -with isolated exomphalos major-presented post-operatively with pulmonary hypertension, refractory cardiogenic shock (inspite of receiving, a bolus of 10ml/kg, Dopamine and Dobutamine 15mg/kg/min, Adrenaline up to 1mg/Kg/min, Noradrenaline 0.5mg/Kg/min, Terlipressin 20mg/Kg/hour, Milrinone 25mg/Kg/min) and arrhythmia (supraventricular tachycardia). Levosimendan was introduced as an intravenous infusion with an initial rate of 0.1 up to 0.2mg/Kg/min in addition to Noradrenaline 1mg/Kg/min, Dopamine 15mg/Kg/min and Furosemide infusion 0.1mg/Kg/hour. The patient improved evidenced by normalization of vital signs and restoration of perfusion with better cardiac functions by echocardiography. Conclusion: Levosimendan has positive inotropic, lusitropic and vasodilating effects for the treatment of heart failure yet further studies in neonates are still required. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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