What Can Gamma Delta T Cells Contribute to an HIV Cure?

Autor: Juno, Jennifer A., Kent, Stephen J.
Předmět:
Zdroj: Frontiers in Cellular & Infection Microbiology; 5/19/2020, Vol. 10, p1-9, 9p
Abstrakt: Elimination of the latent HIV reservoir remains a major barrier to achieving an HIV cure. In this review, we discuss the cytolytic nature of human gamma delta T cells and highlight the emerging evidence that they can target and eliminate HIV-infected T cells. Based on observations from human clinical trials assessing gamma delta immunotherapy in oncology, we suggest key questions and research priorities for the study of these unique T cells in HIV cure research. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index