| Autor: |
Orschulik, Jakob, Hochhausen, Nadine, Czaplik, Michael, Santos, Susana Aguiar, Leonhardt, Steffen, Walter, Marian |
| Předmět: |
|
| Zdroj: |
International Journal of Bioelectromagnetism; Apr2020, Vol. 22 Issue 1, p1-19, 19p |
| Abstrakt: |
The early detection of lung pathologies is crucial to improve the outcome of the patient, especially in critically ill, ventilated patients. For this, a continuous monitoring tool available at the bedside would be appreciated. One possible modality for this is Bioimpedance Spectroscopy (BIS), which measures the complex bioimpedance in a frequency range, typically from a few kHz up to 1 MHz. In this paper, we present the results of an experimental validation study in 17 animals to use bioimpedance measurement for the detection and identification of lung pathologies. Three different groups are investigated: in the first two groups, acute respiratory distress syndrome (ARDS) was induced using either an infusion of lipoplysacharide or repetitive lavages, respectively. The third group served as the control group, where no additional intervention took place. The results of the statistical analysis show that the distribution of impedance magnitude features is significantly different in the two pathological groups compared to the control group. Furthermore, the separation between the two pathological groups seems to be possible by feature combination. Hence, the results indicate that bioimpedance spectroscopy is a promising modality to enable bedside monitoring for lung pathology detection. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
