| Autor: |
Koyama, Teruhisa, Murakami, Motomasa, Nishihara, Osami, Masuda, Toshiki |
| Předmět: |
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| Zdroj: |
Pediatric Dermatology; Sep1996, Vol. 13 Issue 5, p389-393, 5p |
| Abstrakt: |
A newborn girl had some subcutaneous masses within a giant congenital melanocytic nevus in the left parietal area. Microscopic examination revealed melanoma. The tumor consisted of two different patterns, being composed partly of epithelioid cells and partly of spindle-shaped cells. Immunohistochemically the epithelioid cells showed a positive reaction for HMB-45 and NKI/C3, and a negative reaction for desmin and alpha-sarcomeric actin. The spindle-shaped cells showed a negative reaction for HMB-45 and NKI/C3, and a positive reaction for desmin and alpha-sarcomeric actin. Ultrastructurally the spindle-shaped cells had some schwannian features, namely, a basal lamina, interdigitating cell processes, and junctional complexes. The pathologic findings of our case suggest possible direct rhabdomyogenic differentiation of melanoma cells. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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