Comparison between Plasma Electrolytic Oxidation Coating and Sandblasted Acid-Etched Surface Treatment: Histometric, Tomographic, and Expression Levels of Osteoclastogenic Factors in Osteoporotic Rats.

Autor: Momesso, Gustavo Antonio Correia, de Souza Santos, Anderson Maikon, Fonseca e Santos, João Matheus, da Cruz, Nilson Cristino, Okamoto, Roberta, Barão, Valentim Adelino Ricardo, Siroma, Rafael Shinoske, Shibli, Jamil Awad, Perez Faverani, Leonardo
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Zdroj: Materials (1996-1944); Apr2020, Vol. 13 Issue 7, p1604, 1p, 3 Diagrams, 6 Graphs
Abstrakt: Plasma electrolytic oxidation (PEO) has been a promising surface coating with better mechanical and antimicrobial parameters comparing to conventional treatment surfaces. This study evaluated the peri-implant bone repair using (PEO) surface coatings compared with sandblasted acid (SLA) treatment. For this purpose, 44 Wistar rats were ovariectomized (OVX-22 animals) or underwent simulated surgery (SS-22 animals) and received implants in the tibia with each of the surface coatings. The peri-implant bone subsequently underwent molecular, microstructural, bone turnover, and histometric analysis. Real-time PCR showed a higher expression of osteoprotegerin (OPG), receptor activator of nuclear kappa-B ligand (RANKL), and osteocalcin (OC) proteins in the SLA/OVX and PEO/SS groups (p < 0.05). Computed microtomography, confocal microscopy, and histometry showed similarity between the PEO and SLA surfaces, with a trend toward the superiority of PEO in OVX animals. Thus, PEO surfaces were shown to be promising for enhancing peri-implant bone repair in ovariectomized rats. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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