Can IGF-1 Serum Levels Really be Changed by Acute Physical Exercise? A Systematic Review and Meta-Analysis.

Autor: de Alcantara Borba, Diego, da Silva Alves, Eduardo, Rosa, João Paulo Pereira, Facundo, Lucas Alves, Costa, Carlos Magno Amaral, Silva, Aldo Coelho, Narciso, Fernanda Veruska, Silva, Andressa, de Mello, Marco Túlio
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Zdroj: Journal of Physical Activity & Health; May2020, Vol. 17 Issue 5, p575-584, 10p, 5 Diagrams, 3 Charts
Abstrakt: Background: Physical exercise plays an important role in metabolic health, especially in the insulin-like growth factor-1 (IGF-1) system. The objective of this study was to perform a systematic review and meta-analysis to evaluate the effects of a single endurance and resistance exercise session on IGF-1 serum. Methods: The systematic review was performed in SPORTDiscus, MEDLINE, PubMed, and Google Scholar databases. All analyses are based on random-effect models. The study identified 249 records of which 21 were included. Results: There was an effect of endurance exercise on total IGF-1 (P =.01), but not for free IGF-1 (P =.36). Resistance exercise similarly only affected total IGF-1 (P =.003) and not free IGF-1 (P =.37). The effect size indicated that total IGF-1 is more affected (ES = 0.81) by endurance than by resistance exercise (ES = 0.46). The present study showed that IGF-1 serum concentrations are altered by exercise type, but in conditions which are not well-defined. Conclusions: The systematic review and meta-analysis suggest that there is no determinant in serum IGF-1 changes for the exercise load characteristic. Therefore, physical exercise may be an alternative treatment to control changes in IGF-1 metabolism and blood concentration. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index