| Abstrakt: |
Quality of life (QOL) is a personal feeling of health. The quality of life is affected by many factors, in particular, the effect of sinonasal symptoms, which are usually associated with the presence of sinusitis. SNOT-20 (Sinonasal outcome test-20) is one of the most widely used questionnaires for determining the quality of life of patients with sinonasal pathology. This is an independent test with 20 items, for each of which there is a choice of varying degrees of severity of symptoms. SNOT-20 allows comparing the results of treatment in a time interval, as well as the patient's condition for various diseases among themselves. Therefore, to assess the severity and evolution of sinonasal symptoms in patients after endoscopic transsphenoidal surgery, we applied this questionnaire. The purpose of the research: To investigate the influence of various methods of endonasal endoscopic transsphenoidal approaches on the quality of life of patients in the early and late postoperative period. Materials and methods: The study involved 111 patients who underwent endoscopic endonasal transsphenoidal removal of benign sellar tumors. Depending on the technique of approach to the sphenoid sinus, patients were divided into 2 groups. The first group consisted of 45 patients, the surgical treatment of which was carried out according to the generally accepted technique of approach to the sellar region with resection of the mucous membrane of the sphenoethmoidal recess and intranasal structures. Patients who were included in the 2 nd group (64 persons) had a method of approach to the sphenoid sinus by the method we patented. Each group was divided into 2 subgroups, depending on a nasoseptal flap was used or not. All patients were given SNOT-20 questionnaires before and after surgery. According to them, nasal complaints and general complaints of the patient were evaluated. Results: The order model of logistic regression was used to analyze the data obtained. The model concludes the relationship between the result (SNOT-20 estimate) and the forecast (time moment), using the odds ratio. The odds ratio is greater than 1, indicating that the chances for a higher (worst) score are greater than the baseline (pre-operational category). The odds ratio is less than 1 indicates that the chances of increasing the scores below the baseline. The odds ratio close to 1 indicates that there is no difference in points between the postoperative time point and the preoperative line. Conclusions: The results of this initial study confirm the hypothesis that, the sinonasal symptoms are significantly expressed in the early postoperative period after endoscopic endonasal surgery of the anterior skull base, improve over time and reach proximity to the baseline within 6-12 months after surgery. [ABSTRACT FROM AUTHOR] |
