Gram-negative infections in patients with folliculitis decalvans: a subset of patients requiring alternative treatment.

Autor: Samrao, Aman, Mirmirani, Paradi
Předmět:
Zdroj: Dermatology Online Journal; 2020, Vol. 26 Issue 2, p1-4, 4p
Abstrakt: Background: Folliculitis decalvans is a neutrophilic cicatricial alopecia whose etiology remains unknown. It is frequently associated with staphylococcal infections. We aimed to determine the rate of gramnegative infections in patients with folliculitis decalvans. Methods: A retrospective chart review was performed of patients with biopsy-proven folliculitis decalvans seen at a tertiary hair referral center. The results of bacterial cultures were evaluated. Subjects were determined to have no infection, gram-positive infections, gram-negative infections, or mixed infections. Results: Thirty-nine subjects were included in the study. Ninety-three cultures were performed. The majority of cultures were positive for staphylococci. Eleven patients (28%) had gram-negative infections of the scalp. Gram-negative infections comprised one-third of all cultures (33%). Conclusion: We present the largest cohort of folliculitis decalvans patients with gram-negative infections, suggesting the need for routine bacterial cultures in patients who are not responsive to standard anti-staphylococcal antibiotics. Awareness of the incidence of these infections may lead to better therapeutic outcomes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index