| Autor: |
Mane, Priyanka M., Patil, Satish R., Mane, Makarand B., Karande, Geeta S. |
| Předmět: |
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| Zdroj: |
Pravara Medical Review; Sep2019, Vol. 11 Issue 3, p44-52, 9p |
| Abstrakt: |
Introduction: Clostridium difficile antibiotic-associated diarrhoea (CDAD) is a global disease with considerable geographic variation. It has been associated with substantial morbidity and mortality worldwide. Rampant and injudicious use of antibiotics has increased the incidence of Clostridium difficile associated diarrhoea. Aim: To study Clostridium difficile in antibiotic-associated diarrhea Objectives: To study the prevalence of toxin producing Clostridium difficile in antibiotic-associated diarrhea To study the risk factors associated with Clostridium difficile antibiotic-associated diarrhea Material and methods: Laboratory based observational study was carried out on 222 patients with Antibiotic associated diarrhoea. Toxin detection in stool specimens was done by ELISA. Risk factors analysis was done. Results: Prevalence of toxin producing C. difficile was found to be 31.5%. Third generation cephalosporins were the major group of antibiotics causing Antibiotic associated diarrhoea (AAD) 69(31.1%) and CDAD 21(9.5%). Proton pump inhibitors, NSAIDS, Alcohol and Prior hospital stay were found to be significantly associated risk factors causing CDAD. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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