Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARα in fasting mice.

Autor:	Erol, Erdal, Kumar, Leena S., Cline, Gary W., Shulman, Gerald I., Kelly, Daniel P., Binas, Bert
Předmět:	FATTY acid-binding proteins LIVER OXIDATION PEROXISOMES RECEPTOR antibodies FATTY acids
Zdroj:	FASEB Journal; Feb2004, Vol. 18 Issue 2, p347-349, 3p, 3 Graphs
Abstrakt:	Discusses a study on the significance of liver fatty acid binding protein (L-FABP) for hepatic fatty acid oxidation in vivo and for action of peroxisome proliferator-activated receptor α (PPAR&alpha) under fasting condition. Reduction in long chain fatty acid oxidation and ketogenesis in L-FABP null liver; Capacities for long chain fatty acid oxidation and ketogenesis in L-FABP null liver; Hepatic expression of PPARα target genes in fasting L-FABP null mice; Conclusions of the study.
Databáze:	Complementary Index
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