Hay fever: in the laboratory and at natural allergen exposure.
Autor: | Pipkorn, Ulf |
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Předmět: | |
Zdroj: | Allergy; 1988 Supplement 8, Vol. 43, p41-44, 4p |
Abstrakt: | Most laboratory studies have focused on different events associated with an early phase allergic reaction. After an appropriate allergen challenge the immediate response which takes place after a few minutes has an interesting time sequence. The patients start to sneeze within 2-5 minutes after a challenge, thereafter the secretory response starts to emerge and as the last part the nasal blockage is evident and maximal after 10-15 minutes. Several studies have utilized the nasal cavity for the study of allergen-induced mediator release. It has been shown that challenge with allergen induces the release of a whole array of different mediators. |
Databáze: | Complementary Index |
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