| Autor: |
Bergstrand, H., Lundquist, B., Petersson, B.-Å |
| Předmět: |
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| Zdroj: |
Allergy; Jul86, Vol. 41 Issue 5, p319-326, 8p |
| Abstrakt: |
IgE-receptor dependent, but not A23187-induced, histamine release from passively sensitized chopped human lung tissue, or from a dispersed lung cell population obtained from the tissue after enzymatic digestion, is reduced after incubation overnight of cells/ tissue with the glucocorticosteroid budesonide (10-7M). Since the inhibitory effect of budesonide is reduced in the continuous presence of diluted reagin-rich serum used for passive sensitization, but not in the presence of heat-inactivated serum, it is suggested that the glucocorticosteroid acts by reducing the binding of IgE-antibody to the target cell(s). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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