Autor: |
Ledo, A., Martín, M., Geiger, J. M., Marrón, J. M. |
Předmět: |
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Zdroj: |
International Journal of Dermatology; Nov1988, Vol. 27 Issue 9, p656-660, 5p |
Abstrakt: |
A randomized double-blind parallel trial comparing acitretin and etretinate was performed in 20 patients with severe psoriasis during a treatment period of 12 weeks. The initial dose was 30mg/day for 4 weeks, and the mean dose at the end of the study was slightly lower in the acitretin group when compared to the etretinate group (30.7 mg/day and 33.4 mg/day, respectiveIy). Follow-up examinations were carried out every 2 weeks, and the efficacy of treatment was evaluated by using the PASI score. Percentage Improvement in the PASI score was 50% at week 10 in both groups, and the difference between them at week 12 was insignificant. Both quantitatively, and qualitatively, actretin and etretinate do not significantly differ. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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