| Autor: |
Qassam, Shahad A., Ahmed, Zaid K., Nada, Shaymaa Z. |
| Předmět: |
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| Zdroj: |
Iraq Medical Journal (IMJ ); Spring2019, Vol. 3 Issue 2, p37-40, 4p |
| Abstrakt: |
Objectives To study the clinical diagnostic markers and prognostic biochemical markers which helps to evaluate non-alcoholic fatty liver disease (NAFLD) in Iraqi Young adult. Method A total of 816 patients aged 18-40 years were referred for ultrasound checking to detect the prevalence of NAFLD. For comparison of CK18 levels and other studied markers, we chose 45 patients with NAFLD. From the remaining standard individuals, we randomly selected 45 individuals as control group. Blood sample was collected to measure lipid profile, liver enzyme and CK-18. Enzyme linked immuno-sorbent assay used for detecting and quantifying inflammatory markers. Results The results show that serum CK-18 was highly significant in patients with NAFLD when compared with control groups (P = 0.001). Also fatty liver index (FLI) values were significantly higher in patients with NALD than in control group (P =0.001). They also showed markedly great diagnostic accuracy (AUROC curve: 0.968). Conclusion Our result indicates from the results of inflammatory markers that most patients in this study are affected with steatohepatitis, FLI is the most sensitive diagnostic marker for diagnostic NAFLD. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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