Clinical Diagnostic Testing for Human Cytomegalovirus Infections.
| Autor: | Razonable, Raymund R, Inoue, Naoki, Pinninti, Swetha G, Boppana, Suresh B, Lazzarotto, Tiziana, Gabrielli, Liliana, Simonazzi, Giuliana, Pellett, Philip E, Schmid, D Scott |
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| Předmět: |
HUMAN cytomegalovirus diseases
DIAGNOSIS methods HUMAN cytomegalovirus CHILDREN with disabilities KIDNEY transplant complications COMMUNICABLE disease diagnosis CYTOMEGALOVIRUS disease diagnosis CYTOMEGALOVIRUSES NEWBORN screening MOLECULAR diagnosis COMMUNICABLE diseases PRENATAL diagnosis CYTOMEGALOVIRUS diseases PREGNANCY complications ROUTINE diagnostic tests VERTICAL transmission (Communicable diseases) DISEASE management TRANSPLANTATION of organs tissues etc. ALGORITHMS INFECTIOUS disease transmission |
| Zdroj: | Journal of Infectious Diseases; 2020 Supplement, Vol. 221, pS74-S85, 12p |
| Abstrakt: | Human cytomegalovirus (HCMV) infections are among the most common complications arising in transplant patients, elevating the risk of various complications including loss of graft and death. HCMV infections are also responsible for more congenital infections worldwide than any other agent. Congenital HCMV (cCMV) infections are the leading nongenetic cause of sensorineural hearing loss and a source of significant neurological disabilities in children. While there is overlap in the clinical and laboratory approaches to diagnosis of HCMV infections in these settings, the management, follow-up, treatment, and diagnostic strategies differ considerably. As yet, no country has implemented a universal screening program for cCMV. Here, we summarize the issues, limitations, and application of diagnostic strategies for transplant recipients and congenital infection, including examples of screening programs for congenital HCMV that have been implemented at several centers in Japan, Italy, and the United States. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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