β-Thalassemia Major Association with Human Leukocyte Antigen (HLA) Genes in the Malaysian Population.

Autor: Asuar, Wan Nurul Ain Mat, Koyou, Haily Liduin, Lai, Too Chun, Esa, Ezalia, Mustafa, Norhazlin, Mansor, Salawati, Zakaria, Muhammad Zhafri, Tee, Koay Bee, Ismail, Jamiila, Fahmy, Norfarhana Khairul, Arip, Masita
Předmět:
Zdroj: Hemoglobin; Nov2019, Vol. 43 Issue 6, p345-345, 1p
Abstrakt: -Thalassemia major ( -TM) is an inherited blood disorder where affected patients need lifelong blood transfusions. No association was observed in HLA-A and HLA-DRB1 genes with -TM in this study. Our study showed that the HLA-B*46 allele was positively associated with -TM, while HLA-B*60 was negatively associated with this disease in the Malaysian population. [Extracted from the article]
Databáze: Complementary Index