| Autor: |
Hargreave, F. E., Popov, T., Kidney, J., Dolovich, J. |
| Předmět: |
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| Zdroj: |
Allergy; 1993 Supplement 17, Vol. 48, p81-83, 3p |
| Abstrakt: |
The article presents information about the sputum measurements to assess airway inflammation in asthma. Examination of sputum provides a direct method to investigate airway inflammation noninvasively. When sputum cannot be produced spontaneously, it usually can be successfully induced by the inhalation of an aerosol of hypertonic saline. Sputum cell counts can be reproducible, reliable and valid. New methods of examination using cytospins of dithiothreitol treated sputum improve reliability and reduce the time of examination. The cells can also be stained immunohistochemically for activation markers and the cell supernatant can be used to investigate fluid-phase constituents. The use of sputum allows for repeated measurements and the study of severe diseases. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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