17β-Hydroxysteroid dehydrogenase 1:2 and breast cancer recurrence: a Danish population-based study.

Autor:	Collin, Lindsay J., Ulrichsen, Sinna P., Ahern, Thomas P., Goodman, Michael, McCullough, Lauren E., Waller, Lance A., Bang Christensen, Kristina, Damkier, Per, Hamilton-Dutoit, Stephen, Lauridsen, Kristina L., Yacoub, Rami, Christiansen, Peer M., Ejlertsen, Bent, Sørensen, Henrik Toft, Cronin-Fenton, Deirdre P., Lash, Timothy L.
Předmět:	BREAST tumor diagnosis DISEASE relapse CONFIDENCE intervals DRUG resistance ESTRADIOL IMMUNOHISTOCHEMISTRY OXIDOREDUCTASES STATISTICAL sampling TAMOXIFEN MULTIPLE regression analysis POSTMENOPAUSE DATA analysis software TISSUE arrays ODDS ratio POPULATION-based case control
Zdroj:	Acta Oncologica; Mar2020, Vol. 59 Issue 3, p329-333, 5p, 2 Charts
Abstrakt:	The article discusses that breast cancer is the most commonly diagnosed malignancy among women. It mentions that women diagnosed with non-metastatic oestrogen receptor (ER) breast cancer typically receive adjuvant therapy with tamoxifen or aromatase inhibitors; and also mentions that breast carcinomas with increased expression of HSD17B1 compared with HSD17B2 have increased intratumoral concentrations of oestradiol.
Databáze:	Complementary Index
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