Validity and reliability of the reflux symptom score.

Autor: Lechien, Jérôme R., Bobin, Francois, Muls, Vinciane, Thill, Marie‐Paule, Horoi, Mihaela, Ostermann, Katharina, Huet, Kathy, Harmegnies, Bernard, Dequanter, Didier, Dapri, Giovanni, Maréchal, Marie‐Therese, Finck, Camille, Rodriguez Ruiz, Alexandra, Saussez, Sven, Thill, Marie-Paule, Maréchal, Marie-Therese
Zdroj: Laryngoscope; Mar2020, Vol. 130 Issue 3, pE98-E107, 10p
Abstrakt: Objectives/hypothesis: To develop and validate the Reflux Symptom Score (RSS), a self-administered patient-reported outcome questionnaire for patients with laryngopharyngeal reflux (LPR).Study Design: Prospective controlled study.Methods: A total of 113 patients with LPR were enrolled and treated with diet and 3 months of pantoprazole, alginate, and/or magaldrate depending on the LPR characteristics (acid, nonacid, or mixed). Eighty asymptomatic individuals completed the study. Patients and controls completed the RSS twice within a 7-day period to assess test-retest reliability. Internal consistency was measured using Cronbach's α for the RSS items in patients and controls. Validity was assessed by comparing the baseline RSS with the Reflux Symptom Index (RSI) and Voice Handicap Index (VHI). Seventy-seven patients completed the RSS at baseline and after 6 and 12 weeks of treatment to assess responsiveness to change. The RSS cutoff for determining the presence and absence of LPR was examined by receiver operating characteristic analysis.Results: Test-retest reliability (rs = 0.921) and internal consistency reliability (α = 0.969) were high. RSS exhibited high external validity indicated by a significant correlation with the RSI (rs = 0.831). Internal validity was excellent based on the higher RSS in patients compared with controls (P = .001). RSS, RSI, and VHI scores significantly improved from pre- to posttreatment, indicating a high responsiveness to change. RSS >13 can be considered suggestive of LPR-related symptoms. RSS was not influenced by the occurrence of gastroesophageal reflux disease, LPR subtypes, or patient characteristics.Conclusions: RSS is a self-administered patient-reported outcome questionnaire that demonstrates high reliability and excellent criterion-based validity. RSS can be used in diagnosing and monitoring LPR disease.Level Of Evidence: 3b Laryngoscope, 130:E98-E107, 2020. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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