PEG-400 assisted Kröhnke synthesis of 2-(2-hydroxyphenyl)-4-arylpyridines annulated by C5-C6 cycles with substituted benzylidene group.

Autor: Batalin, Sergey, Golikova, Margarita, Khrustaleva, Alexandra, Pchelintseva, Nina
Zdroj: Synthetic Communications; 2020, Vol. 50 Issue 5, p659-668, 10p, 4 Diagrams, 3 Charts
Abstrakt: A simple and efficient method has been developed for the synthesis 2-(2-hydroxyphenyl)-4-arylpyridines annulated by C5-C6 cycles with substituted benzylidene group is achieved by multi-component Kröhnke-type reaction with moderate to good yields in PEG-400. The classical version was considered using cross-conjugated dienones as substrates by counter synthesis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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