| Autor: |
Gerasimidis, Thomas, Papanikolaou, Christos, Kamparoudis, Apostolos, Mavroudis, Aimilios, Karamanos, Dimitrios, Papanikolaou, Athanasios, Gerasimidis, Simeon |
| Předmět: |
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| Zdroj: |
Surgical Chronicles; 2019, Vol. 24 Issue 4, p168-172, 5p |
| Abstrakt: |
The cause of death of a historical figure with the magnitude of Alexander the Great has at times engaged great interest in scholars from different fields. The many opinions are derived so far from historical evidence as well as interpretation of myth-like clues. Our research focused on examination of the signs and symptoms mentioned and interpreted both by ancient (mainly Arrian and Plutarchus) as well as later scholars. The symptom onset was acute abdominal pain after a lavish meal and wine drinking followed by fever and day-by-day progressive, fatal deterioration over 14 days. Research through medical interpretation and the principles of evidence based medicine led us to conclude, that the world's greatest military leader died from a severe intra-abdominal infection, due to acute pancreatitis progressing to necrotizing pancreatitis and obstruction of the bile duct with possible cholangiitis secondary to an inflamed head of the pancreas and severe sepsis. Through differential diagnosis, other possible and proposed causes; such as malaria, pneumonia or pulmonary abscess, typhoid fever, poisoning, withering after Hephaestion's death, West Nile fever and Guillain-Barré syndrome, were excluded. However, undisputable findings still remain to be uncovered, once and if Alexander's tomb and mummified body are found and undergo forensic examination and autopsy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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