| Autor: |
Faujdar, Sameer S., Bisht, Dakshina, Sharma, Amisha |
| Předmět: |
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| Zdroj: |
Journal of Family Medicine & Primary Care; Jan2020, Vol. 9 Issue 1, p180-186, 7p |
| Abstrakt: |
Introduction: The present study was done to access the antibacterial activity of clove (Syzygium aromaticum) against extended‑spectrum beta‑lactamase (ESBL), metallo‑beta‑lactamase (MBL), and AmpC beta‑lactamase‑producing gram‑negative bacteria causing urinary tract infection. Methods: A total of 221 gram‑negative uropathogens were isolated and screened for beta‑lactamase (ESBL, MBL, and AmpC) production and further tested against ethanolic extract of clove (S. aromaticum) for its antibacterial activity. Results: Clove was effective against all gram‑negative isolates but the best antibacterial activity was shown against Proteus species with 19 mm zone of inhibition, 0.39 mg/ml minimum inhibitory concentration (MIC) and 0.19 mg/ml minimum bactericidal concentration (MBC). Conclusions: Clove extract showed different antibacterial potential against all gram‑negative uropathogens. Clove activity for particular strain was found to be similar between isolates producing beta‑lactamase and non beta‑lactamase. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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