| Autor: |
Kraevaya, Olga A., Peregudov, Alexander S., Godovikov, Ivan A., Shchurik, Elena V., Martynenko, Vyacheslav M., Shestakov, Alexander F., Balzarini, Jan, Schols, Dominique, Troshin, Pavel A. |
| Předmět: |
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| Zdroj: |
Chemical Communications; 1/25/2020, Vol. 56 Issue 8, p1179-1182, 4p |
| Abstrakt: |
We report unprecedented Friedel–Crafts arylation of chlorofullerenes C60Cl6 and C70Cl8 with unprotected carboxylic acids as an efficient single-step synthesis of the inherently stable water-soluble fullerene derivatives. Using this method, a series of previously unaccessible compounds was obtained without chromatographic purification in almost quantitative yields. Promising anti-HIV activity comparable to characteristics of commercial drugs was demonstrated for some of these compounds. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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