| Autor: |
Khalife-Hachem, Sabine, Pegliasco, Jean, Saada, Véronique, Hernandez, Eric, Camara-Clayette, Valerie, Cotteret, Sophie, Benabdelali, Raouf, de Botton, Stephane, Marzac, Christophe, Micol, Jean-Baptiste |
| Předmět: |
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| Zdroj: |
Annals of Hematology; Feb2020, Vol. 99 Issue 2, p353-354, 2p |
| Abstrakt: |
We report a fast-morphologic leukemia-free state (MLFS) associated with spontaneous molecular response in a patient with an IDH2 mutant acute myeloid leukemia (AML). Considering patient's poor performance status, and the discordance in the BM results, we decided to withhold the initiation of chemotherapy and performed a 3rd BM aspirate; cytogenetic and NGS were not performed at this time point. Figure 1 shows the longitudinal VAF profiling of the I IDH2 R140Q i mutation in parallel to the percentage of BM blasts. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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