Targeted Delivery of Nucleic Acids by Folate-Containing Liposomes into KB-3-1 and HEK 293 Cells.

Autor: Shmendel, E. V., Kabilova, T. O., Morozova, N. G., Zenkova, M. A., Maslov, M. A.
Předmět:
Zdroj: Russian Journal of Bioorganic Chemistry; Nov2019, Vol. 45 Issue 6, p719-725, 7p
Abstrakt: Targeted cationic liposomes containing folate lipoconjugates with spacer groups of various lengths and natures were prepared; their physicochemical characteristics and their transfection activity towards KB-3-1 and HEK 293 cells were determined. Targeted delivery of plasmid DNA was studied by competitive inhibition of DNA delivery in the presence of free folic acid. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index