| Abstrakt: |
The phenomenon of transepithelial elimination was proposed in 1968, supported by observation of this process in various pathologic states. In eczematous dermatitis leukocytes, erythrocytes and occasionally mast cells transmigrate into the epidermis through a break in the basement membrane and are carried up within the intercellular spaces. In calcinosis cutis, nodular type or secondary to contact with calcium chloride, the epidermis shows areas of pseudoepitheliomatous hyperplasia engulfing masses of calcified material and occasionally forms channels through which particles of calcified material are moved to the surface. |
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