| Autor: |
Macedo da Silva, Rakel Olinda, Gonçalves Castro, José Walber, de Menezes Dantas Junior, Orlando, Justino de Araújo, Ana Carolina, do Nascimento Silva Leandro, Maria Karollyna, Oliveira Costa, Raíra Justino, Leite Pinto, Luciely, Garcia Leandro, Lívia Maria, Silva, Luiz E. da, do Amaral, Wanderlei, Parabocz, Lucas D., Ferriani, Aurea P., Garcia, Bruna, Sales Maia, Beatriz H. L. N., Esmeraldo Rocha, Janaína, Fonseca Bezerra, Camila, Sampaio de Freitas, Thiago, Socorro Costa, Maria, Ferreira Campina, Fábia, Ferreira Matias, Edinardo Fagner |
| Předmět: |
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| Zdroj: |
Antibiotics (2079-6382); Dec2019, Vol. 8 Issue 4, p242, 1p |
| Abstrakt: |
The objective of this work was to evaluate the phytochemical composition and the antibacterial and antibiotic-modulating activities of the essential oils of Eugenia brasiliensis Lam (OEEb) and Piper mosenii C. DC (OEPm) singly or in association with blue LED (Light-emitting diode) light. The antibacterial and antibiotic-modulatory activities of the essential oils on the activity of aminoglycosides were evaluated to determine the minimum inhibitory concentration (MIC, μg/mL) in the presence or absence of exposure to blue LED light. The chemical analysis showed α-pinene and bicyclogermacrene as major constituents of OEPm, whereas α-muurolol was the main compound of OEEb. Both OEEb and OEPm showed MIC ≥ 512 μg/mL against the strains under study. However, the association of these oils with the blue LED light enhanced the action of the aminoglycosides amikacin and gentamicin. In conclusion, the association of aminoglycosides with the blue LED light and essential oils was effective against resistant bacteria. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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