| Autor: |
ЧЕРНЕВА, Р., ЧЕРНЕВА, Ж., ГОСПОДИНОВА, М., ДЕНЧЕВ, С., ПЕТКОВ, Р. |
| Zdroj: |
Medical Review - Cardiovascular Diseases; 2018, Vol. 49 Issue 1, p16-21, 6p |
| Abstrakt: |
Subclinical diastolic dysfunction (SDD) is defined as left ventricular diastolic dysfunction without signs of congestive heart failure and with normal ejection fraction. Despite the limited number of trials, there is enough data for the frequency of SDD, as well as for its progression to symptomatic heart failure. Patients with diabetes, ischaemic heart disease and arterial hypertension have accelerated progression of diastolic dysfunction to clinically overt heart failure as there is an increased risk of mortality. A similar but not so strong association in patients with COPD and anemia is also established. The last group of patients share overlapping symptoms like (breathlessness, fatigue) with diastolic dysfunction, which deters its early diagnosis, especially in patients without cardiovascular risk factors. The understanding of the mechanism, progression and the early detection of the subclinical diastolic dysfunction in patients with COPD will be worthy. This will in favor of the therapeutic strategy for reduction of the morbidity and mortality, associated with the development of heart failure in these patients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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