The Search for a Predictor of CD4 Cell Count Continues: Total Lymphocyte Count Is Not a Substitute for CD4 Cell Count in the Management of HIV-Infected Individuals in a Resource-Limited Setting.

Autor: Akinola, N. O., Olasode, O., Adediran, I. A., Onayemi, O., Murainah, A., Irinoye, O., Elujoba, A. A., Durosinmi, M. A.
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Zdroj: Clinical Infectious Diseases; 8/15/2004, Vol. 39 Issue 4, p579-581, 3p
Abstrakt: Total lymphocyte count (TLC) has been recommended as a substitute for CD4 cell count for the management of HIV-infected individuals living in resource-limited settings. To confirm this, 151 TLCs and CD4 cell counts were obtained from 109 patients who had not yet started treatment and analyzed. CD4 cell counts of <200 cells/mm³ were found in 42 cases (37.8%) with TLCs of ⩾200 cells/mm³. Thus, I in 3 individuals would have been deprived of needed treatment. Therefore, in this setting, TLC is not a reliable predictor of CD4 cell count in HIV-infected individuals. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index