Preliminary Evaluation of Selected Aptamers against Hantaviruse.

Autor: Valdez, E. C. N., Cortez, C. M., dos Santos Oliveira, R. P. O., Vidal, S., Silva, D., de Lemos, E. R. S., Missailidis, S. S.
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Zdroj: AIP Conference Proceedings; 2019, Vol. 2186 Issue 1, p130009-1-130009-3, 3p
Abstrakt: Hantavirus is a zoonotic, viral respiratory disease and is recent associated with human diseases that need a qualitative diagnosis method to promote a rational treatment as well as controlling the spread ability of the virus. Thus a early rational treatment is necessary in the outcome of the disease that on a identification etiological agent is essential. This paper shows results obtained from hantavirus aptamers interaction with the hantavirus protein, ANDES solution, throw fluorometric methods, that will assist in the determination of a secure path to aim an identification mechanism to identify the virus. The investigation revels that aptamer C2526 shows a high affinity binding with hantavirus protein, ANDES, being a promise reactive for recognizing assays. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index