A Model of Microfilaments: Myosin Movement and Axonal Transport.

Autor: Melkikh, A. V., Sutormina, M. I., Babajanyan, S. G., Zafirov, E. A.
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Zdroj: AIP Conference Proceedings; 2019, Vol. 2174 Issue 1, p020189-1-020189-6, 6p
Abstrakt: The mechanism of movement of the myosin heads along the actin filament is described. Based on the assumption that in the excited state of the enzyme (achieved when interacting with ATP), the probability of displacement of one head of myosin is less than the probability of displacement of the other head of myosin, a simplified theoretical model of the movement of myosin with two heads along the actin filament due to ATP hydrolysis was constructed. The expression for the flux of the ATP hydrolysis reaction during the movement of myosin is obtained, which explicitly includes the driving forces of the reaction. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index