TOSMIC REAGENT: AN EXCELLENT PRECURSOR IN THE SYNTHESIS OF BIOLOGICALLY ACTIVE HETEROCYCLES.

Autor: Aderohunmu, Damilola V., Odutola, Taiwo T., Ajani, Olayinka O., Adebiyi, Ezekiel F.
Předmět:
Zdroj: Rasayan Journal of Chemistry; Oct-Dec2019, Vol. 12 Issue 4, p1919-1926, 8p
Abstrakt: Heterocycles are a major material in the world today, with a wide range of applications which include pharmaceutical, cosmetics, reprography, information storage, plastics, solvents, antioxidants, corrosion inhibition among others. The p-toluenesulfonylmethyl isocyanide (TosMIC) is a rich-rewarding synthetic agent making it valuable template in diverse synthetic applications. Synthetic utilization of TosMIC reagent as a precursor for accessing diverse heterocyclic compounds is worthy of note in the domain of applied research. This study is, therefore, tailored at a review of the progress of the TosMIC reagent as a starting material in the synthesis of heterocycles with well-endowed pharmacological activities. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index